Three past champions are on the US Open lineup Friday, with Novak Djokovic, Rafael Nadal and Marin Cilic all seeking to move on to the round of 16.

The No. 1-ranked Djokovic, didn’t have to play in the second when his opponent withdrew with an injury, takes on 61st-ranked Mikhail Youzhny in a third-round match in Arthur Ashe Stadium. He will face Britain’s Kyle Edmund or John Isner in the last 16 in New York. Djokovic, who has been troubled by a wrist injury in recent months, was on court for only 32 minutes.

No. 4-seeded Nadal faces Youzhny’s doubles partner, Andrey Kuznetsov, on Ashe at night, while No. 7 Cilic plays No. 26 Jack Sock of the United States in Louis Armstrong Stadium.

On the women’s side in Ashe, second-seeded Angelique Kerber, the Australian Open champ, faces 17-year-old American qualifier CiCi Bellis. And former No. 1 Caroline Wozniacki – down to No. 74 in the rankings thanks to injury issues and early exits at tournaments – takes on No. 58 Monica Niculescu.